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  5. Tocris Bioscience™ Mirabegron

Tocris Bioscience™ Mirabegron
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Código de producto. 18777116
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Cantidad:
5 mg
25 mg
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25 miligramos
5 miligramos
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Product Code. Cantidad unitSize
18777116 25 mg 25 miligramos
18798936 5 mg 5 miligramos
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Product Code. 18777116 missing translation for 'mfr' Tocris Bioscience™ missing translation for 'supplierNo' 7070/25

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Description

Potent and selective β3 agonist

Mirabegron is a potent and selective β3-adrenoceptor agonist (EC50 = 22.4 nM). Displays >440-fold selectivity for β3 over β1 and β2 adrenoceptors. Increases cAMP concentration in CHO cells expressing human β3-adrenoceptor. Displays relaxant effect in ex vivo rat bladder muscle preparation precontracted with carbachol (Cat. No. 2810). Decreases frequency of bladder contraction in rats. Also promotes browning of white adipose tissue, reduces body weight, and improves glucose tolerance and insulin sensitivity in mice fed a high fat diet.
TRUSTED_SUSTAINABILITY

Specifications

Nombre del producto químico o material 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
CAS 223673-61-8
Cantidad 25 mg
Fórmula molecular C21H24N4O2S
Pureza 98%
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