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  6. MFN1 Mouse anti-Human, Clone: 3F11C11, Proteintech

MFN1 Mouse anti-Human, Clone: 3F11C11, Proteintech

Código de producto. p-7213385 Tienda Proteintech Productos
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Cantidad:
150 μL
20 μL
Unit Size:
150 microlitros
20 microlitros
Product Code. Cantidad unitSize
16848965 20 μL 20 microlitros
16838965 150 μL 150 microlitros
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Product Code. 16848965

Brand: Proteintech 667761IG20UL

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Description

Mouse Monoclonal Antibody

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Specifications

Antígeno MFN1
Aplicaciones Western Blot, Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon 3F11C11
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
génica MFN1
N.º de referencia del gen Q8IWA4
Alias de gen DKFZp762F247, FLJ20693, Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
Símbolos de los genes MFN1
Especie del huésped Mouse
Inmunógeno MFN1 Fusion Protein Ag4890
Método de purificación Protein A
Cantidad 20 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 55669
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG2a
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