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Invitrogen™ MCP-1 Monoclonal Antibody (E10051)
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Código de producto. 11814351
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Cantidad:
500 μg
Tamaño de la unidad:
500 microgramos
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11814351 500 μg 500 microgramos
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Código de producto. 11814351 Proveedor Invitrogen™ N.º de proveedor MMCP1I

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Descripción

Mouse Monoclonal Antibody

MMCP1I targets MCP-1 in ELISA, and WB applications and shows reactivity with Human samples. The MMCP1I immunogen is recombinant human MCP-1. MMCP1I detects MCP-1 which has a predicted molecular weight of approximately 9 kDa. This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg).

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno MCP-1
Aplicaciones ELISA, Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon E10051
Concentración 1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative; pH 7.2
génica Ccl2
N.º de referencia del gen P13500
Alias de gen Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Símbolos de los genes Ccl2
Especie del huésped Mouse
Inmunógeno Recombinant human MCP-1.
Método de purificación Protein G
Cantidad 500 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6347
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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