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Tocris Bioscience™ Lopinavir
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Produktkod. 18775986
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Cantidad:
50 mg
Förpackningsstorlek
50 miligramos
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Produktkod. Cantidad unitSize
18775986 50 mg 50 miligramos
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Produktkod. 18775986 missing translation for 'mfr' Tocris Bioscience™ missing translation for 'supplierNo' 7052/50

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Beskrivning

Highly potent and selective HIV-1 protease inhibitor

Lopinavir is a highly potent and selective HIV-1 protease inhibitor (IC50 = 6.5 nM, HIV cultured in peripheral blood mononuclear cells; Ki = 1.3 pM). Displays >105-fold selectivity for HIV-1 protease over mammalian proteases including renin and cathepsin D and E. Inhibits HIV-1 protease in patient HIV isolates displaying mutations that confer resistance to ritonavir (Cat. No. 5856) (IC50 values in 5 - 50 nM range). Also inhibits SARS-CoV-2 replication in vitro (IC50 = 26 μM)
TRUSTED_SUSTAINABILITY

Specifikationer

Nombre del producto químico o material (αS)-N-[(1 S,3 S,4 S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2 H)-pyrimidineacetamide
CAS 192725-17-0
Cantidad 50 mg
Objetivo Additional Synthetic Protease Inhibitors
Fórmula molecular C37H48N4O5
Pureza 0.98
Produkttitel
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