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Tocris Bioscience™ KYA 1797K

Description
KYA 1797K is a Wnt/β-catenin signaling inhibitor (IC50 = 0.75 μM). Increases binding affinity of β-catenin for axin, GSK-3β and β-TrCP. Promotes formation of the destruction complex, activation of GSK-3β and phosphorylation of β-catenin and K-Ras, leading to their degradation via the ubiquitin/proteasome system. Reduces levels of β-catenin and K-Ras and inhibits growth of colorectal cancer (CRC) cells in vitro and in mouse xenograft models.
Specifications
Specifications
| Nombre del producto químico o material | (5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt |
| CAS | 1956356-56-1 |
| Cantidad | 25 mg |
| Fórmula molecular | C17H11KN2O6S2 |
| Pureza | 98% |
Product Title
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