Heidolph™ Kugelmeiers 3D Cell Culture Plate SP5D (Sphericalplate 5D)

The patented geometry with special coating allows the integration of every single cell into a 3D-agglomerate in a controlled way. This is how uniformly sized spheroids grow without the formation of necrotic cores. The reproducibility of follow-up tests increases, since the experiments always start under identical initial conditions due to the low size variance of the cultivated spheroids.

• According to the size and scale of the experiments, you can choose between our 24-well plate or our 6-well plate
• For small batches, Heidolph™ suggests using the 24-well plate containing 12 wells with 750 microwells each so you will be able to yield up to 9000 uniform spheroids
• You can comfortably carry out monolayer comparative studies in the remaining 12 wells of the same plate
• 6-well plate is suitable for scale-up trials and bigger batches; you can expect a yield of 3364 spheroids per well, thus a total yield of 20,184 spheroids/plate
• The ready to use SP5D is particularly user-friendly: The cultivation does not require any pretreatment or centrifugation steps after seeding your cells
• The media change is also particularly convenient due to simple pipetting, since the height of the microwells was chosen so that the cell clusters are retained
• Platform is compatible with standard automation units