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Tocris Bioscience™ JZL 184
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Product Code. 18045802
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Cantidad:
10 mg
50 mg
Unit Size:
10 miligramos
50 miligramos
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18045802 10 mg 10 miligramos
18065312 50 mg 50 miligramos
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Product Code. 18045802 Supplier Tocris Bioscience™ Supplier No. 3836/10

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Description

Potent MAGL inhibitor

Potent and selective MAGL inhibitor. Blocks hydrolysis of the endocannabinoid 2-arachidonyl glycerol (2-AG) in vivo in the mouse brain (IC50 = 8 nM). Potentiates depolarization-induced suppression of excitability in cerebellar Purkinje neurons. Exhibits >300-fold selectivity for MAGL over FAAH in vitro. Attenuates nociception in neuropathic and inflammatory pain models. Also reduces free fatty acid levels in primary tumors.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1101854-58-3
Fórmula molecular C27H24N2O9

Specifications

Nombre del producto químico o material JZL 184
Cantidad 10 mg
Formula Weight (peso de la fórmula) 520.49
Pureza >98%
Peso molecular 520.494
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