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Itraconazole, MedChemExpress

Código de producto. 16407356
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100 mg
500 mg
Tamaño de la unidad:
100 miligramos
500 miligramos
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16461876 500 mg 500 miligramos
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Código de producto. 16407356 Proveedor Medchem Express N.º de proveedor HY17514100mg

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Descripción

MedChemExpress Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Especificaciones

Nombre del producto químico o material Itraconazole
Forma física Solid
CAS 84625-61-6
Color Blanco
Cantidad 100 mg
Notas de grado de pureza Research
Fórmula molecular C35H38Cl2N8O4
Para utilizar con (aplicación) COVID-19-immunoregulation
Sinónimo R51211
Información de solubilidad DMSO : 6.25 mg/mL (8.86 mM; Need ultrasonic)
SMILES ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
Peso molecular (g/mol) 705.63
Formula Weight (peso de la fórmula) 705.63
Porcentaje de pureza 99.15%
Grado Research
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Research purposes only

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