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PeproTech IL-2 Polyclonal Antibody, PeproTech®, Invitrogen™

Código de producto. 17894333
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Cantidad:
1 mg
100 μg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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17894333 50 μg 50 microgramos
17834153 100 μg 100 microgramos
17804253 1 mg 1 miligramo
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Código de producto. 17894333 Proveedor PeproTech N.º de proveedor 500P11150UG

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Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-2. Anti-Murine IL-2-specific antibody was purified by affinity chromatography employing an immobilized Murine IL-2 matrix. Sandwich ELISA: To detect Murine IL-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine IL-2 (500-P111Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-2. Western Blot: To detect Murine IL-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine IL-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno IL-2
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica IL2
N.º de referencia del gen P04351
Alias de gen aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Símbolos de los genes IL2
Especie del huésped Rabbit
Inmunógeno E.coli-derived Recombinant Murine IL-2.
Método de purificación Antigen affinity chromatography
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 16183
Especies diana Mouse
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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