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Invitrogen™ Human Factor X Native Protein

Código de producto. 11544111
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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Código de producto. Cantidad unitSize
11544111 100 μg 100 microgramos
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Código de producto. 11544111 Proveedor Invitrogen™ N.º de proveedor RP43072

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Descripción

Native Protein

RP-43072 contains native human Factor X protein purified from blood/plasma. RP-43072 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!.

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P00742
Concentración 4.8 mg/mL
Para utilizar con (aplicación) Neutralization
Formulación 50% water with 50% glycerol and no preservative
ID de gen (Entrez) 2159
Peso molecular 58.9 kDa
Nombre Human Factor X
Método de purificación SDS-PAGE
Cantidad 100 μg
Fuente Human
Requisitos de almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Estado normativo RUO
Alias de gen Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor 10; Factor X heavy chain; Factor X light chain; factor Xa; Factor10; FX; FXA; prothrombinase; RP11-98F14.9; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Nombre común Factor X
Símbolo de gen F10
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Formulario Liquid
Subtipo de proteína Native
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