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Invitrogen™ Human Btk Synthetic Peptide

Código de producto. 15266419
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Cantidad:
50 μg
Tamaño de la unidad:
50 microgramos
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Código de producto. Cantidad Tamaño de la unidad
15266419 50 μg 50 microgramos
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Código de producto. 15266419 Proveedor Invitrogen™ N.º de proveedor PEP0203
 Artículo restringido
Fecha estimada de envoi: 02-10-2026
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Description

Synthetic Peptide

This peptide corresponds to 16 amino acids near the amino terminus of human BTK (NT). PEP-0203 can be used as a blocking peptide with polyclonal antibody PA5-20085.

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 695
Especie Human
Método de purificación purified
Número de acceso Q06187
Nombre común BTK
Concentración 200 μg/mL
Contenido y almacenamiento -20°C
Descripción Synthetic Peptide
Formato Liquid
Formulación PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Para utilizar con (aplicación) Blocking Assay, Control
Alias de gen agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency
Símbolo de gen BTK
Liofilizado No
Conservante Sodium azide
Tipo de producto Peptide
Cantidad 50 μg
Estado normativo RUO
Tampón de almacenamiento PBS
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