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Halofuginone, MedChemExpress

Código de producto. 16491648
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16491648 5 mg 5 miligramos
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Código de producto. 16491648 Proveedor Medchem Express N.º de proveedor HYN1584

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Description

MedChemExpress Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM.

Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.

Specifications

Nombre del producto químico o material Halofuginone
Forma física Solid
CAS 55837-20-2
Color Blanco
Cantidad 5 mg
Notas de grado de pureza Research
Fórmula molecular C16H17BrClN3O3
Para utilizar con (aplicación) COVID-19-anti-virus
Sinónimo RU-19110
Información de solubilidad DMSO : 20 mg/mL (48.23 mM; ultrasonic and adjust pH to 5 with HCl)
SMILES O=C1N(CC(C[C@@H]2NCCC[C@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3
Peso molecular (g/mol) 414.68
Formula Weight (peso de la fórmula) 414.68
Porcentaje de pureza 98.03%
Grado Research
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Research purposes only

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