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  6. Epredia™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody

Código de producto. 12659136 Tienda Epredia Productos
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Cantidad:
100 μL
500 μL
1 mL
7 mL
12 mL
Formulario:
Concentrated
Prediluted
Ready-to-Use
Tamaño de la unidad:
1 ml
100 microlitros
12 ml
500 microlitros
7 ml
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Código de producto. Cantidad Formulario unitSize
12659136 500 μL Concentrated 500 microlitros
12649136 100 μL Concentrated 100 microlitros
12639136 1 mL Concentrated 1 ml
12629136 7 mL Prediluted 7 ml
12619136 12 mL Ready-to-Use 12 ml
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Product Code. 12659136 Supplier Epredia™ Supplier No. MS1157S1

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Description

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Granzyme B Ab-1, Mouse Monoclonal Antibody.

Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified. One of these, human granzyme B, is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. Exocytosis of granzyme-containing granules in the cytoplasm of the target cell leads to the induction of DNA fragmentation and apoptosis.

Host Species: Mouse

Clone: GZB01

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: Recombinant protein encoding the N-terminus of the mature granzyme B

Molecular Weight: 32 kDa

Positive Control: Hodgkin's lymphoma, Tonsil

Cellular Localization: Granular cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
TRUSTED_SUSTAINABILITY

Specifications

Antígeno Granzyme B Ab-1
Aplicaciones Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon GZB01
Conjugado Unconjugated
Especie del huésped Mouse
Inmunógeno Recombinant protein encoding the N-terminus of the mature granzyme B
Método de purificación Hodgkin's lymphoma
Cantidad 500 μL
Estado normativo IVD
Disciplina de investigación Apoptosis
Primario o secundario Primary
Especies diana Human
Formulario Concentrated
Isotype IgG2a
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