Gr-1 (Ly-6G/Ly-6C) Rat, anti-Mouse, PE, Clone: RB6-8C5, STEMCELL Technologies

Rat Monoclonal Antibody

Marca: Stemcell Technologies 60028PE.1

Código de producto. 17108611

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Descripción

The RB6-8C5 antibody reacts with the structurally related murine Ly-6G (21 - 25 kDa) and Ly-6C (14 - 16 kDa) GPI-anchored proteins, which together comprise the granulocyte receptor-1 antigen (Gr-1)
Gr-1 is expressed on monocytes, neutrophils, subsets of macrophages, plasmacytoid dendritic cells, and T cells
Monocytes in the bone marrow transiently express Gr-1 during development and the expression level is strongly correlated with granulocyte differentiation and maturation
In the periphery Gr-1 is found predominantly on neutrophils and is a useful marker for these cells
Whereas the RB6-8C5 binds to both Ly-6G and Ly-6C, another commonly used anti-Gr-1 antibody, clone 1A8, binds specifically to Ly-6G
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Neutrophil Enrichment Kit (Catalog #19762)

Especificaciones

Antígeno	Gr-1 (Ly-6G/Ly-6C)
Clasificación	Monoclonal
Conjugado	PE
Cantidad	50 μg
Especies diana	Mouse
Tipo de célula	Granulocytes and Subsets, Monocytes, Myeloid Cells

Aplicaciones	Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry
Clon	RB6-8C5
Especie del huésped	Rat
Primario o secundario	Primary
Isotype	IgG2b κ

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