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Tocris Bioscience™ Givinostat hydrochloride

Descripción
Givinostat hydrochloride is a histone deacetylase (HDAC) inhibitor (IC50 = 7.5 to 16 nM). At low concentrations reduces release of pro-inflammatory cytokines, including TNFα, INFγ, IL-1α and IL-1β, from LPS stimulated PBMCs in vitro. Exhibits anti-inflammatory effects in vivo. Improves functional recovery and attenuates tissue damage in a mouse model of traumatic brain injury.
Specifications
Specifications
| Nombre del producto químico o material | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| CAS | 199657-29-9 |
| Intervalo de porcentaje de ensayo | >98% |
| Cantidad | 5 mg |
| Fórmula molecular | C24H27N3O4.HCl |
| Formula Weight (peso de la fórmula) | Observed MW: 457.95 |
Product Title
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