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PeproTech GDNF Polyclonal Antibody, PeproTech®, Invitrogen™
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Código de producto. 17863353
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Cantidad:
1 mg
100 μg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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17863353 100 μg 100 microgramos
17853353 50 μg 50 microgramos
17843723 1 mg 1 miligramo
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Código de producto. 17863353 Proveedor PeproTech N.º de proveedor 500P81100UG

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Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human GDNF. Anti-Human GDNF-specific antibody was purified by affinity chromatography employing an immobilized hHuman GDNF matrix. Sandwich ELISA: To detect Human GDNF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human GDNF (500-P81Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human GDNF. Western Blot: To detect Human GDNF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human GDNF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
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Especificaciones

Antígeno GDNF
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica GDNF
N.º de referencia del gen P39905
Alias de gen AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Símbolos de los genes GDNF
Especie del huésped Rabbit
Inmunógeno E.coli-derived Recombinant Human GDNF.
Método de purificación Antigen affinity chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 2668
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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