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Invitrogen™ GDF15 Monoclonal Antibody (41)
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Código de producto. 30019941
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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30019941 100 μL 100 microlitros
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Código de producto. 30019941 Proveedor Invitrogen™ N.º de proveedor MA552093

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Mouse Monoclonal Antibody

GDF15 Monoclonal Antibody for IHC (P)

GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno GDF15
Aplicaciones Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon 41
Concentración 100 μg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica Gdf15
N.º de referencia del gen Q99988
Alias de gen Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF
Símbolos de los genes Gdf15
Especie del huésped Mouse
Inmunógeno Recombinant human GDF15 Protein (Ala197-Ile308).
Método de purificación Protein A
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 9518
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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