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Descripción
Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
Especificaciones
Especificaciones
| Antígeno | FTO |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | FTO |
| N.º de referencia del gen | Q8BGW1, Q9C0B1 |
| Alias de gen | FTO, KIAA1752 |
| Símbolos de los genes | FTO |
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Título del producto
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