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Invitrogen™ ERCC1 Polyclonal Antibody

Descripción
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat stomach tissue, mouse stomach tissue, human Hela whole cell, human MCF-7 whole cell, human COLO-320 whole cell.
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot).
Especificaciones
Especificaciones
| Antígeno | ERCC1 |
| Aplicaciones | ELISA, Western Blot |
| Clasificación | Polyclonal |
| Concentración | 500 μg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 4mg trehalose and 0.05mg sodium azide |
| génica | ERCC1 |
| N.º de referencia del gen | P07903, P07992 |
| Alias de gen | COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511 |
| Símbolos de los genes | ERCC1 |
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Título del producto
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