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  8. Dexamethasone 21-phosphate disodium salt, 98%

Dexamethasone 21-phosphate disodium salt, 98%

Código de producto. 15466189
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Código de producto. 15466189 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J64083.03
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Descripción

Dexamethasone 21-phosphate disodium salt, CAS # 2392-39-4, is a synthetic adrenal glucocorticoid with potent anti-inflammatory activity. | CAS: 2392-39-4 | C22H28FNa2O8P | 516.41 g/mol

Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Dexamethasone 21-phosphate disodium salt is a sodium phosphate salt form of dexamethasone, considered to be a synthetic adrenal glucocorticoid with anti-inflammatory activity

Application

  • Dexamethasone 21-phosphate disodium salt binds to specific nuclear steroid receptors, interfering with NF-kB activation and apoptotic pathways
  • It acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter
  • It has been used as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 in the induced reactivation and spontaneous shedding rabbit models
  • This compound is used to study its protective effects against cisplatin-induced ototoxicity in the inner ear of guinea pigs
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 2392-39-4
Fórmula molecular C22H28FNa2O8P
Peso molecular (g/mol) 516.41
Número MDL MFCD00079105
Clave InChI PLCQGRYPOISRTQ-FCJDYXGNSA-L
Sinónimo dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
PubChem CID 16961
ChEBI CHEBI:4462
Nombre IUPAC Disodio;fosfato de [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihidroxi-10,13,16-trimetil-3-oxo-6,7,8,11,12,14,15,16-octahidrociclopenta[a]fenantren-17-il]-2-oxoetil]
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

Especificaciones

Nombre del producto químico o material Dexamethasone 21-phosphate disodium salt
Punto de fusión 233°C to 240°C
Color Blanco
Cantidad 1 g
Beilstein 6473066
Índice Merck 142943
Información de solubilidad Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
Formula Weight (peso de la fórmula) 516.4
Porcentaje de pureza 98%
Forma física Powder

RUO – Research Use Only

Título del producto
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