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Deucravacitinib, MedChemExpress

Código de producto. 16471127
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Product Code. Cantidad unitSize
16471127 50 mg 50 miligramos
16455656 100 mg 100 miligramos
16424878 10 mg 10 miligramos
16403276 25 mg 25 miligramos
16437627 5 mg 5 miligramos
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Product Code. 16471127

Brand: Medchem Express HY117287

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Description

MedChemExpress Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways.

Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways.

Specifications

Nombre del producto químico o material Deucravacitinib
CAS 1609392-27-9
Color Light Yellow
Notas de grado de pureza Research
Fórmula molecular C20H19D3N8O3
Cantidad 50 mg
Sinónimo BMS-986165
Información de solubilidad DMSO : 37.5 mg/mL (88.14 mM; Need ultrasonic)
SMILES O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]
Peso molecular (g/mol) 425.46
Formula Weight (peso de la fórmula) 425.46
Porcentaje de pureza 98.44%
Grado Research
Forma física Solid
Para utilizar con (aplicación) COVID-19-immunoregulation
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Research purposes only

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