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Invitrogen™ CYP1A1/CYP1A2 Monoclonal Antibody (MC1)
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Código de producto. 11525752
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
11525752 100 μL 100 microlitros
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Código de producto. 11525752

Marca: Invitrogen™ MA3036

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Descripción

Mouse Monoclonal Antibody

MA3-036 detects Cytochrome P450 1A1/1A2 from human, primate, rat and mouse samples. MA3-036 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunohistochemisty (paraffin) applications. By Western blot, this antibody detects a ~58 kDa band representing Cytochrome P450 1A1/1A2. The MA3-036 immunogen is 3-methylcholanthrene induced rat cytochrome P450 protein.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CYP1A1/CYP1A2
Aplicaciones Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon MC1
Concentración Conc. Not Determined
Conjugado Unconjugated
Formulación Ascites with 0.05% sodium azide
génica CYP1A2
N.º de referencia del gen P00184, P00185, P00186, P04798, P04799, P05177
Alias de gen AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP11; CP12; CYP1; Cyp1a1; Cyp1a-1; CYP1A2; Cyp1a-2; Cyp45c; Cypc45c; CYPD45; CYPIA1; CYPIA2; Cytochrome P(3)450; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; Cytochrome P3 450; cytochrome P-448; cytochrome P450 1A1; Cytochrome P450 1A2; cytochrome P450 4; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily A member 2; cytochrome P450 family 1 subfamily a polypeptide 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, family 1, subfamily a, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; cytochrome P450-C; Cytochrome P-450d; Cytochrome P450-D; Cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; cytochrome P450-P1; Cytochrome P450-P2; cytochrome P450-P3; dioxin-inducible; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P3-450; P-448; P450 form 4; P450(PA); P450-1; P450-3; P450-C; P-450d; P450-D; P450DX; P450form6; P-450MC; P450MT2; RATCYPD45; xenobiotic monooxygenase
Símbolos de los genes CYP1A1, CYP1A2
Especie del huésped Mouse
Inmunógeno 3-methylcholanthrene induced rat cytochrome P450 protein.
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 13076, 13077, 1543, 1544, 24296, 24297
Especies diana Human, Mouse, Monkey, Rat
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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