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  5. Tocris Bioscience™ CP 43

Tocris Bioscience™ CP 43
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Código de producto. 18773459
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Cantidad:
10 mg
50 mg
Tamaño de la unidad:
10 miligramos
50 miligramos
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Código de producto. 18773459 Proveedor Tocris Bioscience™ N.º de proveedor 6558/10

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Description

Potent TAOK inhibitor

CP 43 is a potent TAO kinase (TAOK) inhibitor (IC50 values are 11 nM/L and 15 nM/L for TAOK1 and TAOK2, respectively). Inhibits TAOK phosphorylation and activation of JNK in vitro. Prolongs duration of mitosis and increases mitotic cell death in the SKBR3 breast cancer cell line. Also reduces tau phopshorylation in cortical neurons at sites associated with neurodegeneration in human tauopathies.
TRUSTED_SUSTAINABILITY

Specifications

Nombre del producto químico o material N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1′-biphenyl]-4-carboxamide
CAS 850467-66-2
Cantidad 10 mg
Fórmula molecular C25H24N2O2
Pureza 98%
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