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Ceritinib dihydrochloride, MedChemExpress

Código de producto. 16452807
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Código de producto. Cantidad unitSize
16452807 50 mg 50 miligramos
16449277 5 mg 5 miligramos
16446866 100 mg 100 miligramos
16436728 10 mg 10 miligramos
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Product Code. 16452807

Brand: Medchem Express HY15656A

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MedChemExpress Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride (LDK378 dihydrochloride) shows great antitumor potency.

Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride (LDK378 dihydrochloride) shows great antitumor potency.

Specifications

Nombre del producto químico o material Ceritinib dihydrochloride
CAS 1380575-43-8
Color Light Yellow
Notas de grado de pureza Research
Fórmula molecular C28H38Cl3N5O3S
Cantidad 50 mg
Sinónimo LDK378 dihydrochloride
Información de solubilidad DMSO : 100 mg/mL (158.46 mM; Need ultrasonic) ∣H2O : 10 mg/mL (15.85 mM; Need ultrasonic)
SMILES CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3.[H]Cl.[H]Cl
Peso molecular (g/mol) 631.06
Formula Weight (peso de la fórmula) 631.06
Porcentaje de pureza 99.0%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-Kinase/protease
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Research purposes only

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