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Invitrogen™ CD69 Monoclonal Antibody (8B6)

Descripción
MA5-15612 targets CD69 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples. The MA5-15612 immunogen is purified recombinant fragment of human CD69 expressed in E. Coli. MA5-15612 detects CD69 which has a predicted molecular weight of approximately 22.5kDa.
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
Especificaciones
Especificaciones
| Antígeno | CD69 |
| Aplicaciones | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Monoclonal |
| Clon | 8B6 |
| Concentración | Conc. Not Determined |
| Conjugado | Unconjugated |
| Formulación | Ascites with 0.03% sodium azide |
| génica | CD69 |
| N.º de referencia del gen | Q07108 |
| Alias de gen | 5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen |
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Título del producto
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