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CD51 (Integrin αV) Mouse, anti-Human, PE, Clone: NKI-M9, STEMCELL Technologies

Código de producto. 17108751
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Cantidad:
100 Tests
25 Tests
Tamaño de la unidad:
100 tests
25 tests
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17198741 100 Tests 100 tests
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Código de producto. 17108751 Proveedor Stemcell Technologies N.º de proveedor 60043PE.1

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Mouse Monoclonal Antibody

  • The NKI-M9 antibody reacts with CD51 (vitronectin receptor α chain, or integrin αV), a type I transmembrane glycoprotein containing two subunits (125 kDa and 24 kDa) which are generated by post-translational cleavage and are linked by a disulfide bond
  • CD51 associates non-covalently with integrin β1 (CD29), β3 (CD61), β5, β6, or β8 to form heterodimeric cell adhesion receptors for extracellular matrix components such as fibrinogen, collagen, fibronectin, laminin, osteopontin, thrombospondin, vitronectin, and von Willebrand factor
  • For example, association of CD51 and CD61 forms the integrin αv/β3 receptor primarily involved in binding vitronectin
  • CD51 is expressed broadly on many types of cells, including endothelial cells, fibroblasts, monocytes, macrophages, platelets (at relatively low levels), and osteoclasts
  • It is also found on hepatoma, melanoma, and neuroblastoma cells

Especificaciones

Antígeno CD51 (Integrin αV)
Aplicaciones Immunoprecipitation, ELISA, Flow Cytometry, Functional Assay
Clasificación Monoclonal
Clon NKI-M9
Conjugado PE
Especie del huésped Mouse
Cantidad 25 Tests
Primario o secundario Primary
Especies diana Human
Isotype IgG2a κ
Tipo de célula Mesenchymal Stem and Progenitor Cells
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