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Invitrogen™ CD263 (TRAIL-R3) Recombinant Rabbit Monoclonal Antibody (003), PE
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Código de producto. 17860986
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Cantidad:
100 Tests
Tamaño de la unidad:
paquete de 100
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17860986 100 Tests paquete de 100
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Código de producto. 17860986 Proveedor Invitrogen™ N.º de proveedor MA546672

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Descripción

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAIL-R3 (CD263) (Met1-Pro235) and conjugated with PE under optimum conditions, the unreacted PE was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
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Especificaciones

Antígeno CD263 (TRAIL-R3)
Aplicaciones Flow Cytometry
Clasificación Recombinant Monoclonal
Clon 003
Concentración 100 μg/mL
Conjugado PE
Formulación PBS with 0.5% BSA and 0.09% sodium azide
génica TNFRSF10C
N.º de referencia del gen O14798
Alias de gen Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; Decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor superfamily member 10c; TNF-related apoptosis-inducing ligand receptor 3; TNFRSF10C; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; UNQ321/PRO366
Símbolos de los genes TNFRSF10C
Especie del huésped Rabbit
Inmunógeno Recombinant protein ecoding Human CD263 (TRAIL-R3) (Met1-Pro235).
Método de purificación Protein A
Cantidad 100 Tests
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 8794
Especies diana Human
Contenido y almacenamiento 4°C, store in dark, DO NOT FREEZE!
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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