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Invitrogen™ CCL5 (RANTES) Monoclonal Antibody (21445), APC
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Código de producto. 15503252 Tienda Thermo Scientific Productos
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Cantidad:
100 Tests
Tamaño de la unidad:
100 tests
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Código de producto. 15503252 Proveedor Invitrogen™ N.º de proveedor MA523557

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Mouse Monoclonal Antibody

In direct ELISAs and Western blots, this antibody does not cross-react with other chemokines, including recombinant human CCL2, 3, 4 recombinant mouse (rm) CCL3, and rmCCL4.

CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CCL5 (RANTES)
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon 21445
Conjugado APC
Formulación Buffered saline solution with BSA and 0.09% sodium azide
génica CCL5
N.º de referencia del gen P13501
Alias de gen beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS δ; SISd; SIS-delta; SISδ; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)
Símbolos de los genes CCL5
Especie del huésped Mouse
Inmunógeno E. coli-derived recombinant human CCL5/RANTES.
Método de purificación Protein A/G
Cantidad 100 Tests
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6352
Especies diana Human
Contenido y almacenamiento 4°C, store in dark, DO NOT FREEZE!
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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