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  6. PeproTech Cardiotrophin 1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

PeproTech Cardiotrophin 1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
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Código de producto. p-7245459
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Cantidad:
2 x 500 μg
25 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
25 microgramos
50 microgramos
500 microgramos
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Código de producto. Cantidad unitSize
17864443 25 μg 25 microgramos
17804063 50 μg 50 microgramos
17884353 2 x 500 μg 1 miligramo
30054745 500 μg 500 microgramos
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Código de producto. 17864443 Proveedor PeproTech N.º de proveedor 500P101BT25UG

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Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: SRREGSLEDP QTDSSVSLLP HLEAKIRQTH SLAHLLTKYA EQLLQEYVQL QGDPFGLPSF SPPRLPVAGL SAPAPSHAGL PVHERLRLDA AALAALPPLL DAVCRRQAEL NPRAPRLLRR LEDAARQARA LGAAVEALLA ALGAANRGPR AEPPAATASA ASATGVFPAK VLGLRVCGLY REWLSRTEGD LGQLLPGGSA. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Cardiotrophin-1. Anti-Human Cardiotrophin-1-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human Cardiotrophin-1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Cardiotrophin-1 (500-P101) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Cardiotrophin-1. Western Blot: To detect hCardiotrophin-1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hCardiotrophin-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P101BT-1MG will be provided as 2 x 500 μg

Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Cardiotrophin 1
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Biotin
Formulación PBS with no preservative
génica CTF1
N.º de referencia del gen Q16619
Alias de gen cardiophin 1; Cardiotrophin; cardiotrophin 1; Cardiotrophin1; cardiotrophin-1; CT 1; CT1; CT-1; CT-1CT1; CTF 1; Ctf1; IL-6 cytokine family
Símbolos de los genes CTF1
Especie del huésped Rabbit
Inmunógeno E.coli-derived Recombinant Human Cardiotrophin-1.
Método de purificación Antigen affinity chromatography
Cantidad 25 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 1489
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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