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Candesartan, 98%

Código de producto. 15405129
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Cantidad:
100 mg
1 g
Unit Size:
1 g
100 miligramos
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Product Code. Cantidad Unit Size
15405129 100 mg 100 miligramos
15495119 1 g 1 g
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Product Code. 15405129 Supplier Thermo Scientific Alfa Aesar Supplier No. J62818.MC
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    66.20€
    59.65€ / 100 miligramos
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Description

Angiotensin II receptor antagonist | CAS: 139481-59-7 | C24H20N6O3 | 440.463 g/mol

Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits vasoconstriction and the production of aldosterone, leading to a decrease in water and sodium concentration in blood plasma. Exhibits antihypertensive effects in animal models. Used in treatment of congestive heart failure, as antihypertensive. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in ethyl acetate, methanol, water (<1mg/mL at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 139481-59-7
Fórmula molecular C24H20N6O3
Peso molecular (g/mol) 440.463
Número MDL MFCD00081076
Clave InChI HTQMVQVXFRQIKW-UHFFFAOYSA-N
Sinónimo candesartan, blopress, ratacand, 1-2'-1h-tetrazol-5-yl-1,1'-biphenyl-4-yl methyl-2-ethoxy-1h-benzo d imidazole-7-carboxylic acid, candesartan ban, 3h candesartan, unii-s8q36md2xx, 2-ethoxy-3-4-2-2h-tetrazol-5-yl phenyl phenyl methyl benzimidazole-4-carboxylic acid, candesartan usan/inn, candesartan usan:inn
PubChem CID 2541
ChEBI CHEBI:3347
Nombre IUPAC 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

Specifications

Nombre del producto químico o material Candesartan
Punto de fusión 183°C to 185°C
Color Blanco
Cantidad 100 mg
Índice Merck 14,1739
Información de solubilidad Soluble in ethyl acetate,methanol,water (<1mg/ml at 25°C),DMSO (88mg/ml at 25°C),and ethanol (1mg/ml at 25°C).
Formula Weight (peso de la fórmula) 440.45
Porcentaje de pureza 98%
Forma física Powder

Safety and Handling

compliance-icons
Product Identifier
  • Candesartan
 Signal Word
  • Atención
 Hazard Category
  • Toxicidad para la reproducción Categoría 2
 Hazard Statement
  • H361d-Se sospecha que daña al feto.
 Precautionary Statement
  • P201-Pedir instrucciones especiales antes del uso.
  • P280-Llevar guantes/prendas/gafas/máscara de protección.
  • P308+P313-EN CASO DE exposición manifiesta o presunta: Consultar a un médico.
 Supplemental information
  • MIXTURE LIST-Contain: Candesartan
SDS

RUO – Research Use Only

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