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  6. Invitrogen™ C5AR1 Monoclonal Antibody (10/92)

Invitrogen™ C5AR1 Monoclonal Antibody (10/92)

Código de producto. 11520053
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Código de producto. 11520053 Proveedor Invitrogen™ N.º de proveedor MA181763

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Descripción

Rat Monoclonal Antibody

For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Rat anti Mouse CD88 antibody, clone 10/92 recognizes murine CD88, a 45 kDa G-protein coupled cell surface receptor, otherwise known as C5aR. Rat anti Mouse CD88 antibody, clone 10/92 recognizes murine CD88, a 45 kDa G-protein coupled cell surface receptor, otherwise known as C5aR.

CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno C5AR1
Aplicaciones Flow Cytometry, Immunohistochemistry (Frozen), Immunocytochemistry
Clasificación Monoclonal
Clon 10/92
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.09% sodium azide; pH 7.4
génica C5AR1
N.º de referencia del gen P30993
Alias de gen anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Símbolos de los genes C5AR1
Especie del huésped Rat
Inmunógeno RBL-2H3 transfected cells expressing murine C5aR.
Método de purificación Protein G
Cantidad 250 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 12273
Especies diana Mouse
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG2a
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