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Bexarotene, 98%, Thermo Scientific Chemicals

Código de producto. 15485879
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Cantidad:
100 mg
Tamaño de la unidad:
100 miligramos
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15485879 100 mg 100 miligramos
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Código de producto. 15485879 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J63701.MC
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Synthetic retinoid analog with specific affinity for the retinoid X receptor

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 153559-49-0
Fórmula molecular C24H28O2
Peso molecular (g/mol) 348.49
Número MDL MFCD00932428
Clave InChI NAVMQTYZDKMPEU-UHFFFAOYSA-N
Sinónimo bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
Nombre IUPAC 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
SMILES CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Especificaciones

Nombre del producto químico o material Bexarotene
Punto de fusión 220°C to 225°C
Color Blanco
Cantidad 100 mg
Índice Merck 14,1194
Información de solubilidad Soluble in DMSO and ethanol
Formula Weight (peso de la fórmula) 348.48
Porcentaje de pureza ≥99%
Forma física Powder

RUO – Research Use Only

Título del producto
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