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Berberine chloride

Código de producto. 15424719
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Cantidad:
5 g
Tamaño de la unidad:
5 g
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Código de producto. 15424719 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J62311.06
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    42.65€ / 5 g
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Description

CAS: 633-65-8 | C20H18ClNO4 | 371.817 g/mol

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethyl sulfoxide (74 mg/ml at 25°C), ethanol (<1mg/mL at 25°C), water (<1mg/mL at 25°C), and methanol.

Notes
Store at -20°C. Incompatible with oxidizing agents. Protect from heat.
TRUSTED_SUSTAINABILITY

Specifications

Nombre del producto químico o material Berberine chloride
CAS 633-65-8
Color Amarillo a naranja
Fórmula molecular C20H18ClNO4
Número MDL MFCD00011939
Cantidad 5 g
Beilstein 3836585
Sinónimo berberine chloride, berberine hydrochloride, natural yellow 18, benzodioxide, berberinium chloride, berberine hcl, unii-uot4o1byv8, berberine chloride jan, uot4o1byv8
Información de solubilidad Soluble in dimethyl sulfoxide (74mg/ml at 25°C),ethanol (<1mg/ml at 25°C),water (<1mg/ml at 25°C),and methanol.
Clave InChI VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
Peso molecular (g/mol) 371.817
PubChem CID 12456
ChEBI CHEBI:31271
Formula Weight (peso de la fórmula) 371.82
Forma física Powder
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