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Invitrogen™ Bcl-XS Polyclonal Antibody

Descripción
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA whole cell, PC-12 whole cell. IHC: Human Colon Cancer Tissue.
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Especificaciones
Especificaciones
| Antígeno | Bcl-XS |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 500 μg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal |
| génica | Bcl2l1 |
| N.º de referencia del gen | P53563, Q07817, Q64373 |
| Alias de gen | anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; BCL2L; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-xl; BCL-XL/S; BCLXS; bcl-xS; Blc2l; PPP1R52; protein phosphatase 1, regulatory subunit 52 |
| Símbolos de los genes | Bcl2l1 |
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Título del producto
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