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Tocris Bioscience™ Azidothymidine
Beskrivelse
Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.
Tekniske data
Tekniske data
| Pureza | 99% |
| Fórmula molecular | 3 '-Azido-3 '-deoxythymidine |
| CAS | 30516-87-1 |
| Contenido y almacenamiento | -20 °C |
| Cantidad | 50 mg |
| Tipo de producto | Azidothymidine |
| Peso molecular | M.W. (Observed): 267.24 |
| Inhibidores | Azidothymidine |
Para uso exclusivo en investigación
Produkttitel
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