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  5. Tocris Bioscience™ AZ PFKFB3 26

Tocris Bioscience™ AZ PFKFB3 26
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Product Code. 30002174
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Cantidad:
10 mg
50 mg
Unit Size:
10 miligramos
50 miligramos
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30002174 10 mg 10 miligramos
30000838 50 mg 50 miligramos
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Product Code. 30002174 Supplier Tocris Bioscience™ Supplier No. 5675/10

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Description

Potent and selective PFKFB3 inhibitor

Potent and selective PFKFB3 inhibitor (IC50 = 0.023 μM). Selective for PFKFB3 over PFKFB2 and PFKFB1 isoforms (IC50 values are 0.382 μM and 2.06 μM, respectively). Reduces levels of fructose-1,6-bisphosphate in A549 cells (IC50 = 0.343 μM). Exhibits no significant inhibition of other kinases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1704740-52-2
Fórmula molecular C24H26N4O2

Specifications

Nombre del producto químico o material (2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide
Cantidad 10 mg
Solubilidad Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight (peso de la fórmula) 402.49
Forma física Solid
Pureza >98%
Peso molecular 402.498
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