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ATG4D Polyclonal Antibody, Invitrogen™
Descripción
A 1:1,000 dilution of PA5-77781 was sufficient for detection of ATG4D in 15 μg of Human HeLa Cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.∣Detects approximately 53 kDa.
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.
Especificaciones
Especificaciones
| Antígeno | ATG4D |
| Aplicaciones | Immunocytochemistry, Western Blot |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.09% sodium azide; pH 7.4 |
| génica | Atg4d |
| N.º de referencia del gen | Q86TL0 |
| Alias de gen | 9830134P12Rik; APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; APG4D; APG4-D; ATG4 autophagy related 4 homolog D; Atg4d; Atg4dl; Autl4; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D cysteine peptidase; autophagy related 4D, cysteine peptidase; autophagy-related 4D; autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine protease ATG4D; Cysteine protease ATG4D, mitochondrial; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D |
| Símbolos de los genes | Atg4d |
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Título del producto
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