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AS601245, MedChemExpress

Código de producto. 16497067
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Cantidad:
5 mg
10 mg
50 mg
Tamaño de la unidad:
10 miligramos
5 miligramos
50 miligramos
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Código de producto. Cantidad unitSize
16497067 5 mg 5 miligramos
16434358 10 mg 10 miligramos
16400687 50 mg 50 miligramos
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Artikelnummer. 16497067 Leverandør Medchem Express Leverandørnr. HY11010

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Beskrivelse

MedChemExpress AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

Tekniske data

Nombre del producto químico o material AS601245
Forma física Solid
CAS 345987-15-7
Color Yellow
Cantidad 5 mg
Notas de grado de pureza Research
Fórmula molecular C20H16N6S
Para utilizar con (aplicación) Cancer-Kinase/protease
Información de solubilidad DMSO : 10 mg/mL (26.85 mM; Need ultrasonic)
SMILES N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3
Peso molecular (g/mol) 372.45
Formula Weight (peso de la fórmula) 372.45
Porcentaje de pureza 98.7%
Grado Research
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Research purposes only

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