missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticuerpos
  4. Anticuerpos primarios
  5. Todos los anticuerpos primarios
  6. 15820109

FR4 (Folate receptor 4) Rat anti-Mouse, APC, Clone: 12A5, BD

Rat Monoclonal Antibody

Marca:  BD Biosciences 560318

Código de producto. 15820109

  • 488.00€ / cada uno

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

Este artículo no se puede devolver. Vea la política de devoluciones

Descripción

Descripción

The monoclonal antibodies TH6 and 12A5 recognize Folate Receptor 4 (FR4), also known as the membrane folate-binding protein 3 (FBP3). FR4 is a heavily glycosylated 35kDa receptor expressed exclusively in lymphoid tissue and an isoform of the family of receptors that recognize the essential nutrient folic acid. Natural T regulatory cells constitutively express high levels of FR4. Differential expression of FR4 in combination with CD25 can distinguish four functionally distinct CD4+ T cell subpopulations; Natural Tregs, effector T cells, memory-like T cells and Nanve T cells. FR4hi CD25+ expressing CD4+ T cells also express high amounts of Foxp3, GITR and CTLA-4. Monoclonal antibody TH6 and 12A5 stained CD25+CD4+ T cells at a higher level than other CD4+ or CD8+ T cells. In addition, in vivo injection of TH6 monoclonal antibody reduced the number of CD25+CD4+ T cells and CD25-CD4+ T cells in peripheral blood. Clone 12A5 has been demonstrated to work in western blot. Clones TH6 and 12A5 do not block one another in a flow cytometric assay.

Host Species: Rat
Clone: 12A5
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse CD4+ CD25+ T cells

Flow Cytometry

TRUSTED_SUSTAINABILITY
Especificaciones

Especificaciones

FR4 (Folate receptor 4)
Monoclonal
0.2mg/mL
Folate receptor 4, FBP, FBP3, FRdelta, FRd
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
12A5
APC
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse CD4+ CD25+ T cells
0.1 mg
Immunology
Mouse
IgG1
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Promociones

Promociones

Corrección del contenido de un producto

Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.

Título del producto

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.