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CD71 Mouse anti-Human, Unlabeled, Clone: M-A712, BD

Código de producto. 15838248
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Cantidad:
0.1 mg
Tamaño de la unidad:
cada uno
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15838248 0.1 mg cada uno
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Código de producto. 15838248 Proveedor BD Biosciences N.º de proveedor 555534
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Fecha estimada de envoi: 10-08-2026
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Descripción

Mouse Monoclonal Antibody

The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR). This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers. CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells. CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens. Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin. After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.

TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CD71
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon M-A712
Concentración 0.5mg/mL
Conjugado Unconjugated
Descripción TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Formulación Aqueous buffered solution containing ≤0.09% sodium azide.
Especie del huésped Mouse
Inmunógeno T-CLL and Jurkat Cells
Método de purificación Affinity Purified
Cantidad 0.1 mg
Estado normativo RUO
Disciplina de investigación Immunology
Primario o secundario Primary
Especies diana Human
Contenido y almacenamiento Store undiluted at 4°C
Isotype IgG2a κ
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