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  7. Amlodipine besylate, 98+%

Amlodipine besylate, 98+%

Código de producto. 15474589
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Código de producto. 15474589 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J62164.14
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Descripción

An L-type calcium channel antagonist with potent antioxidant activity | CAS: 111470-99-6 | C26H31ClN2O8S | 567.05 g/mol

Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

Solubility
Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 111470-99-6
Fórmula molecular C26H31ClN2O8S
Peso molecular (g/mol) 567.05
Número MDL MFCD00887594
Clave InChI ZPBWCRDSRKPIDG-UHFFFAOYSA-N
Sinónimo amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin
PubChem CID 60496
ChEBI CHEBI:2669
Nombre IUPAC benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

Spécification

Nombre del producto químico o material Amlodipine besylate
Punto de fusión 195°C to 204°C
Color Blanco
Cantidad 25 g
Índice Merck 14,491
Información de solubilidad Soluble in DMSO (?20mg/mL),water (10 mM),chloroform,ethanol (?14mg/mL),and methanol.
Formula Weight (peso de la fórmula) 567.05
Porcentaje de pureza ≥98%
Forma física Solid

RUO – Research Use Only

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