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Invitrogen™ ADAP Polyclonal Antibody
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Código de producto. 12868582
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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12868582 100 μg 100 microgramos
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Product Code. 12868582 Supplier Invitrogen™ Supplier No. PA520401

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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20401 can be used with blocking peptide PEP-0518.

The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappa-B family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno ADAP
Aplicaciones Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.02% sodium azide
génica FYB1
N.º de referencia del gen O15117
Alias de gen ADAP; adhesion and degranulation promoting adaptor protein; adhesion and degranulation-promoting adaptor protein; B630013F22Rik; Fyb; Fyb1; FYB-120/130; FYN binding protein; FYN binding protein (FYB-120/130); FYN binding protein FYB-130; FYN-binding protein; FYN-binding protein 1; FYN-T-binding protein; p120/130; p120/p130; PRO0823; RGD1563421; Slap130; SLAP-130; SLP-76-associated phosphoprotein
Símbolos de los genes FYB1
Especie del huésped Rabbit
Inmunógeno A 17 amino acid peptide from near the amino terminus of human ADAP.
Método de purificación Antigen Affinity Chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 2533
Especies diana Human
Contenido y almacenamiento Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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