missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Reactivos para análisis de proteínas
  4. Moléculas pequeñas bioactivas
  5. 18704444

Tocris Bioscience™ a-Synuclein Degrader 2b
GREENER_CHOICE

Código de producto. 18704444
Cambiar vista
Click to view available options
Cantidad:
5 mg
Tamaño de la unidad:
5 miligramos
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Código de producto. Cantidad unitSize
18704444 5 mg 5 miligramos
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Este artículo no se puede devolver. Vea la política de devoluciones
Código de producto. 18704444 Proveedor Tocris Bioscience™ N.º de proveedor 8040/5

Please to purchase this item. Need a web account? Register with us today!

Este artículo no se puede devolver. Vea la política de devoluciones

Description

α-synuclein Degrader (PROTAC™)

α-Synuclein Degrader 2b is a selective α-synuclein Degrader (PROTAC™) (DC50 = 7.5 μM; Dmax = 89%). Comprises the probe molecule sery308, joined by a linker to a pomalidomide E3 ligase ligand. Activates both proteasomal and lysosomal degradation pathways. Protects SH-SY5Y cells from α-synuclein-induced cytotoxicity. Cell permeable.PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
TRUSTED_SUSTAINABILITY

Specifications

Nombre del producto químico o material 2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide
CAS 2781922-42-5
Cantidad 5 mg
Objetivo Active Degraders
Fórmula molecular C39H41N7O10
Pureza 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.