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  5. Tocris Bioscience™ A 438079 hydrochloride

Tocris Bioscience™ A 438079 hydrochloride
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Product Code. 18014842
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Cantidad:
10 mg
50 mg
Unit Size:
10 miligramos
50 miligramos
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18014842 10 mg 10 miligramos
18015682 50 mg 50 miligramos
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Product Code. 18014842 Supplier Tocris Bioscience™ Supplier No. 2972/10

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Description

Competitive P2X7 antagonist

A 438079 hydrochloride is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 > 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 899431-18-6
Fórmula molecular C13H10Cl3N5

Specifications

Nombre del producto químico o material A 438079 hydrochloride
Cantidad 10 mg
Formula Weight (peso de la fórmula) 342.61
Pureza >98%
Peso molecular 342.608
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