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  7. 6(5H)-fenantridinona, 96 %, Thermo Scientific Chemicals

6(5H)-fenantridinona, 96 %, Thermo Scientific Chemicals

Product Code. 11460648
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Cantidad:
1 g
5 g
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1 g
5 g
Product Code. Cantidad unitSize
11460648 1 g 1 g
11470648 5 g 5 g
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Product Code. 11460648

missing translation for 'mfr': Thermo Scientific Alfa Aesar B25187.03

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Description

CAS: 1015-89-0 | C13H9NO | 195.221 g/mol

6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La 6(5H)-fenantridinona se utiliza como sonda con función de PARP en la respuesta celular a la radiación. El tratamiento de las células con 6(5H)-fenantridinona y varios agentes dañinos para el ADN mostró resistencia a la apoptosis. Actúa como reactante en la síntesis de 5,6-dihidrofenantridina sulfonamidas, acoplamiento oxidativo con difenilacetileno, N-ciclopropilación directa catalizada por acetato de cobre de amidas cíclicas. Se utiliza como inhibidor de la integrasa del VIH-1.

Solubilidad
Soluble en DMSO (5 mg/ml). Insoluble en agua.

Notas
Los materiales incompatibles son agentes oxidantes. Almacénese en lugar fresco. Mantenga el recipiente bien cerrado en un lugar seco y bien ventilado.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1015-89-0
Fórmula molecular C13H9NO
Peso molecular (g/mol) 195.221
Número MDL MFCD00004988
Clave InChI RZFVLEJOHSLEFR-UHFFFAOYSA-N
Sinónimo 6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone
PubChem CID 1853
ChEBI CHEBI:75292
Nombre IUPAC 5H-fenantridina-6-ona
SMILES C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O

Specifications

Nombre del producto químico o material 6(5H)-Phenanthridinone
Punto de fusión 288°C to 294°C
Cantidad 1 g
Beilstein 140641
Información de solubilidad Soluble in DMSO (5mg/ml). Insoluble in water.
Formula Weight (peso de la fórmula) 195.22
Porcentaje de pureza 96%

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