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Avanafil, MedChemExpress

Product Code. 16483507
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Cantidad:
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Unit Size:
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500 miligramos
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16483507 50 mg 50 miligramos
16477446 100 mg 100 miligramos
16421896 500 mg 500 miligramos
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Product Code. 16483507 Supplier Medchem Express Supplier No. HY18252

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Description

MedChemExpress Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively.

Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis.

Specifications

Nombre del producto químico o material Avanafil
CAS 330784-47-9
Color Blanco
Notas de grado de pureza Research
Fórmula molecular C23H26ClN7O3
Cantidad 50 mg
Sinónimo TA1790
Información de solubilidad DMSO : 50 mg/mL (103.32 mM; Need ultrasonic)
SMILES COC1=C(Cl)C=C(CNC2=C(C(NCC3=NC=CC=N3)=O)C=NC(N4[C@H](CO)CCC4)=N2)C=C1
Peso molecular (g/mol) 483.95
Formula Weight (peso de la fórmula) 483.95
Porcentaje de pureza 98.0%
Grado Research
Forma física Solid
Para utilizar con (aplicación) COVID-19-immunoregulation
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Research purposes only

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