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  7. 5-(N,N-Hexamethylene)-amiloride, MedChemExpress

5-(N,N-Hexamethylene)-amiloride, MedChemExpress

Código de producto. 16478077
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16478077 5 mg 5 miligramos
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Product Code. 16478077 Supplier Medchem Express Supplier No. HY128067

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Description

MedChemExpress 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells.

5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively.

Specifications

Nombre del producto químico o material 5-(N,N-Hexamethylene)-amiloride
CAS 1428-95-1
Color Light Yellow
Notas de grado de pureza Research
Fórmula molecular C12H18ClN7O
Cantidad 5 mg
Sinónimo Hexamethylene amiloride HMA
Información de solubilidad DMSO : 100 mg/mL (320.75 mM; Need ultrasonic)
SMILES O=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N
Peso molecular (g/mol) 311.77
Formula Weight (peso de la fórmula) 311.77
Porcentaje de pureza 98.0%
Grado Research
Forma física Powder
Para utilizar con (aplicación) Cancer-programmed cell death
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Research purposes only

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