Thermo Scientific™ 5 L DynaDrive™ Bioreactor Bioprocess Consumable (BPC) Puck Sensor Version

The Thermo Scientific™ DynaDrive™ 5 L BioProcess Container (BPC), PROSUT00180-I, is a pre-irradiated, single-use bioreactor container designed for upstream process development and scale-down modeling. Featuring integrated puck sensor technology for pH and dissolved oxygen (DO) measurement, this BPC enables rapid setup, control, and scalability when scaling to the larger DynaDrive family of reactors.

Manufactured with Thermo Scientific™ Aegis™ 5-14 bioprocess film and an integrated multi-impeller DynaDrive drivetrain, the PROSUT00180-I BPC delivers efficient mixing, robust gas transfer capability, and process performance aligned with the full DynaDrive platform from bench scale through 5,000 L working volume.

Key features and benefits

• Mixing, sparging, and geometry principles of larger DynaDrive bioreactors for confident scale-up into DynaDrive family
• Flexible 5:1 turndown ratio (1–5 L)
• Cuboid design with natural fluid baffling effects
• Integrated sensor puck for pH and DO measurements
• Multi-impeller drivetrain and enhanced drilled-hole sparger (DHS) support high cell density cultures with effective DO and CO2 control
• Gamma-irradiated single-use BPC eliminates the need for autoclaving, reducing turnaround time and contamination risk versus traditional glass bioreactors
• Fed-batch & perfusion capable standard design

Typical applications

• Upstream process development and optimization
• Scale-down modeling for fed-batch or perfusion processes
• Media and feed screening
• Seed train and N-1 process development
• Transition from glass benchtop bioreactors to single-use systems

Product specifications (highlights)

• Working volume: 1–5 L (5:1 turndown ratio)
• Film: Thermo Scientific Aegis 5-14 bioprocess film
• Agitation: Integrated DynaDrive multi-impeller drivetrain
• Sparging: Enhanced drilled-hole sparger for efficient oxygen transfer and CO2 stripping and open pipe sparger
• Sensors: Integrated pH and DO sensor puck
• Sterilization: Gamma-irradiated, single-use, ready-to-install
• Compatible with 5 L DynaDrive single-use bioreactor stands configured for puck sensor (DDB0005.1020)
• Compatible with 5L DynaDrive Puck Sensor Probe Kit (F110-2751-001)

Designed for the DynaDrive ecosystem

The PROSUT00180-I BPC is part of the Thermo Scientific DynaDrive Single-Use Bioreactor platform, providing a direct and consistent scalability path from bench-scale development to commercial-scale manufacturing.