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Invitrogen™ 4-1BB Ligand Recombinant Rabbit Monoclonal Antibody (014), APC

Código de producto. 17800656
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Cantidad:
100 Tests
Tamaño de la unidad:
paquete de 100
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Código de producto. Cantidad Tamaño de la unidad
17800656 100 Tests paquete de 100
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Código de producto. 17800656 Proveedor Invitrogen™ N.º de proveedor MA546776
  • ONLINE EXCLUSIVE PRICE
    452.00€
    411.32€ / paquete de 100
    Ahorro 40.68€
    9% Descuento
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Fecha estimada de envoi: 15-12-2026
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Descripción

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse 4-1BBL (CD137L) (Arg104-Glu309) and conjugated with APC under optimum conditions, the unreacted APC was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma). CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno 4-1BB Ligand
Aplicaciones Flow Cytometry
Clasificación Recombinant Monoclonal
Clon 014
Concentración 100 μg/mL
Conjugado APC
Formulación PBS with 0.5% BSA and 0.03% ProClin 300
génica TNFSF9
N.º de referencia del gen P41274
Alias de gen 4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Símbolos de los genes TNFSF9
Especie del huésped Rabbit
Inmunógeno Recombinant protein encoding Mouse 4-1BB Ligand (Arg104-Glu309).
Método de purificación Protein A
Cantidad 100 Tests
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 21950
Especies diana Mouse
Contenido y almacenamiento 4°C, store in dark, DO NOT FREEZE!
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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