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  6. Thermo Scientific Chemicals 2'-Deoxiguanosina

Thermo Scientific Chemicals 2'-Deoxiguanosina

Catalog Number 15453449
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Cantidad:
1 g
5 g
10 g
Este artículo no se puede devolver. Vea la política de devoluciones
961-07-9
C10H13N5O4
267.25
MFCD00150760
YKBGVTZYEHREMT-DWFKHXNSNA-N
2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl
187790
CHEBI:17172
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1
Este artículo no se puede devolver. Vea la política de devoluciones
961-07-9
C10H13N5O4
267.25
MFCD00150760
YKBGVTZYEHREMT-DWFKHXNSNA-N
2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl
187790
CHEBI:17172
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Descripción

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La deoxiguanosina (dG) es un nucleósido purínico que al realizar la fosforilación secuencial (quinasas) forma dGTP que es utilizado por las polimerasas de ADN y las transcriptasas inversas para sintetizar el ADN. La deoxiguanosina es la más rica en electrones de las cuatro bases canónicas e incluye muchos sitios nucleofílicos que son susceptibles al daño oxidativo. Esto hace que la deoxiguanosina y sus derivados oxidados sean reactivos útiles para estudiar los mecanismos de daño oxidativo a los nucleósidos y los nucleótidos.

Solubilidad
Soluble en NH4OH 1 M: 50 mg/ml, de transparente a muy ligeramente turbio.

Notas
Almacenar en un lugar fresco. Mantener el recipiente bien cerrado en un lugar seco y bien ventilado. Almacenar lejos de los agentes oxidantes fuertes.
TRUSTED_SUSTAINABILITY
Nombre del producto químico o material 2'-Deoxyguanosine
Color Blanco
Cantidad 10 g
Información de solubilidad Soluble in NH4OH 1 M: 50mg/mL,clear to very faintly turbid.
Formula Weight (peso de la fórmula) 285.26 (267.25 Anhydrous)
Forma física Polvo cristalino

RUO – Research Use Only

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